The April 2003 CAST-convened symposium on pest resistance management (PRM) was the first such U.S.-based multidisciplinary stakeholder meeting in nearly a decade. Major objectives included identifying common issues related to PRM across disciplines, considering ways to remove barriers to effective preventive resistance management, describing research activities in PRM, and disseminating this information to a wide audience of stakeholders. Fifty-two presentations are collected in this proceedings.